Purity >95%. N1,N12 -Acetylspermine is a diacetylated derivative of spermine , an endogenous polyamine synthesized from spermidine , that displays lower Km and higher Vmax values than spermine, making it a better substrate of polyamine oxidase than the non-acetylated polyamine. Spermine is required for eukaryotic cell growth and protein synthesis and is involved in the modulation of calcium-dependent immune processes. Upregulation of N1,N12 -acetylspermine has been linked to the incidence of cancer, making this natural polyamine a potential biomarker for cancer detection.
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Other Names
N,N'-[1,4-butanediylbis(imino-3,1-propanediyl)]bis -acetamide, dihydrochloride, BAS