NAP-2 (Neutrophil Activating Peptide 2) is a member of the CXC chemokine family. It is similar to other ELR domain containing chemokines to CXC receptors such as interleukin-8 and GRO proteins. NAP-2 binds to CXCR-2 and chemoattracts and activates neutrophils. NAP-2 is a proteolytically processed carboxyl-terminal fragment of platelet basic protein (PBP) and is found in the -granules of human platelets.
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