Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1)
Clone
Ada-1
Host Species
Mouse
Reactive Species
human, rat
Isotype
IgG2a
Format
ascites
Size
100 μg
Concentration
n/a
Applications
Western Blotting (WB)
Reviews / Ratings
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Description
Alpha Adaptin, also known as adaptor related protein complex, alpha 1 subunit. The alpha adaptins are exclusively found in the endocytic coated vesicles. Huntingtin-interacting protein 1(HIP1) is enriched in membrane-containing cell fractions and has been implicated in vesicle trafficking. Waelter et al.(2001) identified 3 HIP1-associated proteins, clathrin heavy chain(CLTC)and alpha-adaptin A and C. Coat proteins of approximately 100-kD(adaptins) are components of the adaptor complexes which link clathrin to receptors in coated vesicles. The alpha-adaptins separate into two bands on SDS gels.