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Description
Mouse Anti-DIABLO Recombinant Antibody (CBXS-2606). This product is a mouse antibody that recognizes DIABLO. The antibody CBXS-2606 can be used for immunoassay techniques such as: ELISA, WB. This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms.
Immunogen
Recombinant protein corresponding to aa56-239 from human SMAC
Other Names
Diablo IAP-Binding Mitochondrial Protein; Second Mitochondria-Derived Activator Of Caspase; Direct IAP-Binding Protein With Low PI; SMAC; Diablo, IAP-Binding Mitochondrial Protein; Diablo Homolog, Mitochondrial; Diablo-Like Protein; DFNA64;