PPP1R8, Recombinant, Human, aa1-209, GST-Tag (Nuclear Inhibitor of Protein Phosphatase 1)
Description
Purity ~90% (SDS-PAGE). Inhibitor subunit of the major nuclear protein phosphatase-1 (PP-1). It has RNA-binding activity but does not cleave RNA and may target PP-1 to RNA-associated substrates. May also be involved in pre-mRNA splicing. Binds DNA and might act as a transcriptional repressor. Seems to be required for cell proliferation. Isoform Gamma is a site-specific single-strand endoribonuclease that cleaves single strand RNA 3' to purines and pyrimidines in A+U-rich regions. It generates 5'-phosphate termini at the site of cleavage. This isoform does not inhibit PP-1. May be implicated in mRNA splicing. Source: Recombinant protein corresponding to aa1-209 from human PPP1R8, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~52.1kD AA
Size
10ug, 50ug, 100ug
Concentration
n/a
Applications
n/a
Other Names
Protein phosphatase 1 regulatory inhibitor subunit 8