Purity: > 95% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 7.5) containing 20% glycerol, 1mM DTT, 0.1M NaCl, 0.1mM PMSF. The SIRT6 is included in class IV of the sirtuin family, homologs to the yeast Sir2 protein. The functions of human sirtuins have not yet been determined; however, in yeast sirtuins are known to regulate epigenetic gene silencing. Also SIRT6, a chromatin-associated protein, appears to be involved in DNA repair. Recombinant SIRT6, fused to His-tag at N-terminus, was expressed in E.coli and purified by conventional chromatography techniques.
Size
0.5mg, 100ug, 20ug
Concentration
n/a
Applications
SDS-PAGE
Other Names
Sirtuin 6, SIR2L6, Mono-ADP-ribosyltransferase sirtuin-6, SIR2-like protein 6, Sirtuin 6 Mono ADP ribosyltransferase sirtuin 6, SIR2 like protein 6, Sir2 related protein type 6, SIRT 6, Sirtuin (silent mating type information regulation 2 homolog) 6 (S, cerevisiae), Sirtuin 6, Sirtuin type 6, Sirtuin6.