ELISA, Western Blot. Each kit contains one unit of the following products: (100 μL) p/n 100-401-191 Anti-RFX5 (C-terminal) (RABBIT) Antibody(100 μL) p/n 100-401-194 Anti-RFX5 (aa 320 to 494) (RABBIT) Antibody(100 μL) p/n 100-401-193 Anti-RFX5 (N-terminal) (RABBIT) Antibody(100 μg) p/n 611-1322-0100 Anti-RABBIT IgG (H&L) (GOAT) Antibody Peroxidase Conjugated
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Description
RFX5 Antibody detects the RFX5 protein. Regulatory factor X subunit 5 (RFX5) is a member of a family of DNA-binding proteins that share a novel and highly characteristic DNA-binding domain called the RFX motif. It mediates cooperative binding between RFX and NF-Y, recognizes X-boxes, and activates transcription from class II MHC promoters. RFX5 mutations are seen in cases of a severe immunodeficiency syndrome called MHC-II deficiency (also known as bare lymphocyte syndrome (BLS)). These mutations prevent the RFX complex from binding to the X box in MHC-II promoters, resulting in a lack of MHC-II expression. Anti-RFX5 antibody is ideal for investigators involved in cytokines and growth factor research.