DNA was prepared from cell line WM983BBR. WM983BBR is a human metastatic melanoma cell line that displays a mesenchymal morphology. The WM983BBR cell line contains the BRAF V600E mutation that causes increased signaling via the extracellular signal-regulated MAPK/ERK kinase pathways to enhance proliferation. WM983BBR is wild type for PTEN, N-ras, c-KIT, and CDK4. This cell line was derived from the same pateint as the cell lines WM983A, WM983B, and WM983C. The WM983BBR cells produce xenograft tumors when injected into immunocompromised mice.
Size
10 μg
Concentration
200 ng / μl
Applications
Purified Genomic DNA is suitable for a number of molecular biology applications including but not limited to preparation of genomic libraries, PCR templates, DNA sequencing, DNA fingerprinting, and mutation analysis.
Other Names
Human Melanoma, patient derived tumor, tumor models, skin cancer, xenograft