Immunoglobulin E (IgE) is found in human secretions and fluids, such as respiratory tract mucus and saliva, urine, tears, human milk as well as in intestinal juices. It is responsible for various immediate hypersensitivity reactions like Type-I-hypersensitivity. Antigens trigger B-cells to produce and release IgE in large amounts which bind to the Fc receptor on the surface of mast cells. The next time the sensitized person has contact to the allergen, it cross links the IgE on the surface of the mast cells and thereby triggers the mast cells to release histamine, which cause the various symptoms. IgE is involved in a number of allergic phenomena such as erythema,anaphylaxis, skin-sensitization, and atopic reaction. In subjects suffering from allergy, the IgE levels increase as much as three to four times compared to the healthy. Sample Types: Human plasma, serum, stool. Sample Size: 20 μL. Range: 0.31-20 kU/L. Sensitivity: 0.31 kU/L. Time: 2hr 10min
Size
96 wells
Concentration
n/a
Applications
Research Use Only. Not for Use in Diagnostic Procedures.