MW: 35,001 Da. Purity >95%, as determined by SDS-PAGE and HPLC. FcγRIIA is expressed on cells ofboth myeloid and lymphoid lineages as well as on cells of non- hematopoietic origin.Associated with an ITAM (immunoreceptor tyrosine-based activation motif) -bearing adapter subunit,FcRγ,CD32a (FcγRIIA) d elivers an activating signal upon ligand binding,and results in the initiation of inflammatory responses including cytolysis,phagocytosis,degra nulation and cytokine production.The res
? dynamics of the interaction of human igg subtype immune complexes with cells expressing r and h allelic forms of a low-affinity fc receptor CD32a .J. Immunol., Dec 2009; 183: 8216 - 8224. ? association of fcriia (CD32a) with lipid rafts regulates ligand binding activity .J. Immunol., Jun 2009; 182: 8026 - 8036. ? transgenic expression of human platelet fcriia (CD32a) in mice does not affect the thrombocytopenia associated with wasp deficiency. .Blood (ASH Annual Meeting Abstract