Purity ~90% (SDS-PAGE). The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Mediates the lipopolysaccharide-induced signal transduction in the macrophage proteasome. Might be involved in the anti-inflammatory response of macrophages during the interaction with C. albicans heat-inactivated cells. Source: Recombinant protein corresponding to aa1-251 from human PSMA1, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~32.2kD AA