A bulky purine analog that acts as a selective, ATP-competitive, analog-sensitive Plk1 allele inhibitor; blocks mitotic progression in cells expressing analog-sensitive Plk1 alleles at 10 μM and selectively sensitizes Plk1 to small-molecule inhibitors
Size
10 mg
Concentration
n/a
Applications
n/a
Other Names
analog-sensitive kinase alleles protein kinase ATP analog polo-like kinase 1 Plk1 cancer cell-division inhibitor mitosis biochemical intracellular signaling signal transduction 3-MB-PP1 VGG PP1 3 III