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Description
UniProt: P41597 CCR2B is a 374 amino acid protein that belongs to the G protein-coupled receptor 1 family with seven transmembrane domains. It mediates the chemotactic properties of monocyte chemoattractant protein 1 (MCP-1) which is secreted by endothelial and epithelial cells, vascular smooth muscle and hematopoietic cells. MCP-1 is a potent chemoattractant for monocytes and lymphocytes. It is responsible for monocyte infiltration in a variety of chronic inflammatory diseases.
Immunogen
n/a
Other Names
C-C Chemokine Receptor Type 2, Monocyte Chemoattractant Protein 1 Receptor, CD192