Endoglin (CD105) is a type I membrane glycoprotein located on cell surfaces and is part of the TGF beta receptor complex. The protein consists of a homodimer of 180 kDA with disulfide links. It has been found on endothelial cells, activated macrophages, fibroblasts, and smooth muscle cells. Endoglin has been found to be part of the TGF-beta1 receptor complex. It thus may be involved in the binding of TGF-beta1, TGF-beta3, activin-A, BMP-2, and BMP-7. Alternative Names: Mouse Endoglin protein, CD-105, Murine Endoglin protein, CD 105 protein, CD 105, CD-105 protein, Murine CD105 protein, CD105