產(chǎn)品名稱 Ataciguat from CAYMAN CHEMICAL COMPANY
    產(chǎn)品貨號(hào) 16371-10
    產(chǎn)品價(jià)格 現(xiàn)貨詢價(jià)，電話：010-67529703
    產(chǎn)品規(guī)格 10 mg
    產(chǎn)品品牌 CAYMAN CHEMICAL COMPANY
    產(chǎn)品概述
    產(chǎn)品詳情
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    Product NameAtaciguat
    DescriptionAn anthranilic acid derivative that activates the oxidized (heme-free) form of sGC (EC50 = 0.5-10 μM in purified bovine lung or crude human corpus cavernosum) by binding to the heme pocket and mimicking its function; increases cGMP levels in cultured rat aorta smooth muscle cells and induces vasorelaxation of isolated rat aorta, porcine coronary arteries, and human corpus cavernosum isolates (EC50 = 1-10 μM)
    Size10 mg
    Concentrationn/a
    Applicationsn/a
    Other Names254976-06-2 sGC agonists activators oxidized hemes ferric cGMP vasorelaxation solubles guanylates cyclases nitric oxides signaling NO cyclic GMP hypertensions hyperlidemia cardiovascular diseases diabetes anthranilic acids derivatives oxidized heme-free free oxidizes purified bovine lungs crude humans corpus cavernosum binding binds pockets mimicking functions levels cultured rats aorta smooth muscles cells induces isolated porcine coronary arteries activates primary cellular receptors groups conversions GTP seconds messengers cascades inhibiting inhibits inhibitors proliferations leukocytes recruitments platelets aggregations oxidations dissociations impairments nucleotides biochemistry vasculars isolates
    Gene, Accession, CAS #CAS: 254877-67-3
    Catalog #16371-10
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    Order / More InfoAtaciguat from CAYMAN CHEMICAL COMPANY
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