A kainate receptor agonist; binds to GluR5, GluR6, and GluR7 recombinant homomeric kainate receptors (Kis = 2, 6, and 37 nM, respectively), KA-1 and KA-2 kainate receptors, and the GluR4 AMPA receptor; binds to kainate and AMPA receptors in rat forebrain membranes (IC50s = 4.9 and 9.2 nM, respectively); depolarizes primary motor neurons and dorsal root fibers isolated from newborn rats; induces convulsive behavior in rats (ED50 = 0.07 nmol/animal); induces seizures in mice (CD50 = 0.09 nmol/animal)