MW: 555.5. Purity ≥98% by HPLC. Bedaquiline is an anti-tuberculosis drug. Bedaquiline's unique and specific anti-mycobacterial activity derives from inhibition of the proton pump of mycobacterial ATP synthase; which is a critical enzyme in the ATP synthesis of M. tuberculosis. Binding of bedaquiline to the oligomeric and proteolipic subunit-c of mycobacterial ATP synthase leads to inhibition of ATP synthesis; which subsequently results in bacterial death.