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Description
Function: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. Also known as: CACB3, Voltage dependent L-type calcium channel subunit beta-3.
Immunogen
A synthetic peptide from the c-terminal region of rat CACN (CACB3, Voltage dependent L-type calcium channel subunit beta-3) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in mouse and shares 90% identity with human sequence.