Recombinant Human Activating signal cointegrator 1 complex subunit 3 (ASCC3)
Description
Purity > 90% as determined by SDS-PAGE. MW: 40kDa. Full Length of Isoform 2: 1-111aa. N-terminal GST-tagged. Homo sapiens (Human). 3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3, enabling ALKBH3 to process alkylated N3-methylcytosine (3mC) within double-stranded regions. Enhances NF-kappa-B, SRF and AP1 transactivation.