Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) (AA 2-393) (Active) protein (His tag)
Description
MAP2K1 is a member of the dual specificity protein kinase family, which plays a role as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, are recognized as extracellular signal-regulated kinases (ERKs), that act as an integration position for multiple biochemical signals. MEK1 is located upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As a key player of MAP kinase signal transduction pathway, MEK1 is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. MAP2K1 catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a thr-glu-tyr sequence located in map kinases. MEK1 activates erk1 and erk2 map kinases Synonyms: MEK1, MKK1, MAPKK1, MAP2K1, Dual specificity mitogen-activated protein kinase kinase 1, MAP kinase kinase 1, EC 2.7.12.2, ERK activator kinase 1, MAPK/ERK kinase 1, PRKMK1
Size
5 μg
Concentration
n/a
Applications
n/a
Other Names
Mek1|CFC3|MAPKK1|MEK1|MKK1|PRKMK1|MEKK1|Prkmk1|mek-2|si:ch211-242m18.2|wu:fj56a12|wu:fj61b01|zgc:56557|ATMEK1|F20B18.180|F20B18_180|MAP kinase/ ERK kinase 1|MITOGEN ACTIVATED PROTEIN KINASE KINASE|MITOGEN ACTIVATED PROTEIN KINASE KINASE 1|NMAPKK|MEK