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Description
Rabbit IgG polyclonal antibody for Prospero homeobox protein 1(PROX1) detection. Tested with WB in Human;Mouse;Rat. No cross reactivity with other proteins. Prospero homeobox protein 1, also called PROX1 is a protein that in humans is encoded by the PROX1 gene. This gene is mapped to 1q32.3. The protein encoded by this gene is a member of the homeobox transcription factor family. Members of this family contain a homeobox domain that consists of a 60-amino acid helix-turn-helix structure that binds DNA and RNA. The protein encoded by this gene is conserved across vertebrates and may play an essential role during development. Altered levels of this protein have been reported in cancers of different organs, such as colon, brain, blood, breast, pancreas, liver and esophagus.
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human PROX1(346-359aa KHLAETLKQELNTA), identical to the related mouse and rat sequences.
Other Names
Prospero homeobox protein 1;Homeobox prospero-like protein PROX1;PROX-1;PROX1;