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| Antigenic Specificity | Glypican 1 (GPC1) (C-Term) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | antigen affinity purified |
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| Size | 0.1 mg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (IHC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | GPC1(Glypican-1) is a cell surface proteoglycan that bears heparan sulfate. The protein is attached to the membrane by a GPI-anchor. This cell-associated glypican is further processed to give rise to a medium-released species. The glypican-1 is required for efficient TGF-beta1 signaling in pancreatic cancer cells. The syndecan-1 and glypican-1 have roles in progression of ovarian cancer. Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. |
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| Immunogen | Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human GPC1(Glypican-1 precursor) |
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| Other Names | gpc1|zgc:63947|GPC1|Glypican-1|glypican|AI462976|HSPG M12|HSPGM12 |
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| Gene, Accession # | Gene ID: 2817,14733 |
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| Catalog # | ABIN966218 |
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| Price | |
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| Order / More Info | Glypican 1 (GPC1) (C-Term) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 2148568, 15297422, 12972423, 12084716, 11375980, 16723715, 15547662, 11968010, 11454708 |
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