Antitumor agent that forms platinum-DNA adducts. Causes intra- and interstrand DNA crosslinks blocking DNA replication and transcription. Enhances radiation-induced single-strand DNA breakage and displays lower nephrotoxicity than analog cisplatin (Cat. No. 2251). Purity 99%. MW (observed): 371.25
Size
50 mg
Concentration
n/a
Applications
n/a
Other Names
cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II). NSC 241240, Paraplatin, JM 8