Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C)
Clone
34-3C
Host Species
Mouse
Reactive Species
mouse
Isotype
IgG2a
Format
unconjugated
Size
100 μg
Concentration
n/a
Applications
Flow Cytometry (FACS),Functional Studies (Func)
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Description
The monoclonal antibody 34-3C recognizes an exposed surface determinant of intact red blood cells (RBC). The high-affinity anti-RBC monoclonal antibody efficiently bind to Fc receptors on macrophages inducing anemia in vivo due to a rapid Fc receptor (FcyR)-mediated erythrophagocytosis of opsonised RBC in spleen and livers. The capacity of the antibody to interact with FcyR is responsible for its haemolytic activity. The monoclonal antibody only recognises antigenic determinants expressed on Mouse RBC and not on other species of RBC. Immunogen RBC