Human CellExp? LRRC32 / GARP, Fc Tag, Human Recombinant
Description
Leucine-rich repeat protein 32 (LRRC32), also known as GARP (glycoprotein A repetitions predominant). LRRC32 expression promotes the acquisition of a Treg phenotype including reduced cellular proliferation, reduced cytokine secretion, and the capacity to suppress the proliferation of naive T cells. LRRC32 binds directly to the TGF-beta latency associated peptide (LAP) and tethers latent TGF-beta on the surface of activated Treg cells. The presentation of TGF-beta on Tregs contributes to their ability to suppress naive T cell proliferation. MW: 92.6 kDa. Purity > 95%
Size
50 μg
Concentration
n/a
Applications
RUO
Other Names
GARP, Garpin, D11S833E, Glycoprotein A repetitions predominant