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| Antigenic Specificity | NEIL2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 μL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:500-1:3000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NEIL2 Polyclonal Antibody. NEIL2 is involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Has DNA glycosylase activity towards 5-hydroxyuracil and other oxidized derivatives of cytosine with a preference for mismatched double-stranded DNA (DNA bubbles). Has low or no DNA glycosylase activity towards thymine glycol, 2-hydroxyadenine, hypoxanthine and 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. |
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| Immunogen | n/a |
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| Other Names | NEH2, NEI2, nei like DNA glycosylase 2 |
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| Gene, Accession # | Entrez: 252969; Uniprot: Q969S2 |
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| Catalog # | PA5-78662 |
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| Price | |
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| Order / More Info | NEIL2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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