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Description
Rabbit IgG polyclonal Picoband? antibody for ETV6/Tel detection. Tested with WB, IHC-P, Direct ELISA in Human;Mouse;Rat. No cross reactivity with other proteins. Transcription factor ETV6 is a protein that in humans is encoded by the ETV6 gene. This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.
Immunogen
E. coli-derived human ETV6/Tel recombinant protein (Position: E327-Q448).