產(chǎn)品名稱 uPSEM 792 hydrochloride from TOCRIS BIOSCIENCE
    產(chǎn)品貨號(hào) 6865/5
    產(chǎn)品價(jià)格 現(xiàn)貨詢價(jià)，電話：010-67529703
    產(chǎn)品規(guī)格 5 mg
    產(chǎn)品品牌 TOCRIS BIOSCIENCE
    產(chǎn)品概述
    產(chǎn)品詳情
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    Product NameuPSEM 792 hydrochloride
    DescriptionUltrapotent PSEM (uPSEM) agonist for PSAM4-GlyR and PSAM4-5HT3 (Ki = 0.7 nM for PSAM4-GlyR and <10 nM for PSAM4-5HT3). Exhibits >10,000-fold agonist selectivity for PSAM4-GlyR over α7-GlyR, α7-5HT3, and 5HT3-R, and 230-fold selectivity over α4β2 nAChR. Also weak partial agonist (~10 %) at α4β2 nAChR. Retains the potency of varenicline (Cat.No. 3754) for PSAM4-GlyR with enhanced chemogenetic selectivity. Does not act as a substrate for P-glycoprotein pumps. Silences neurons in vivo. Brain-penetrant. Purity 96%. MW (observed): 277.75
    Size5 mg
    Concentrationn/a
    Applicationsn/a
    Other Names1-Methyl-7,8,9,10-tetrahydro-1H-6,10-methanoazepino[4,5-g]quinoxalin-2(6H)-one hydrochloride
    Gene, Accession, CAS #n/a
    Catalog #6865/5
    Price
    Order / More InfouPSEM 792 hydrochloride from TOCRIS BIOSCIENCE
    Product Specific Referencesn/a
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