Recombinant Mouse Acyl-coenzyme A thioesterase 8 (Acot8)
Description
1-320aa, Full length protein. MW: 35,827 Da. Purity >85% (SDS-PAGE). This protein is a peroxisomal thioesterase that appears to be involved more in the oxidation of fatty acids rather than in their formation. The encoded protein can bind to the human immunodeficiency virus-1 protein Nef, and mediate Nef-induced down-regulation of CD4 in T-cells. Multiple transcript variants encoding several different isoforms have been found for this gene.