Solute Carrier Family 1 (Glutamate/Neutral Amino Acid Transporter), Member 4 (SLC1A4) (aa 495-512), (C-Term)
Clone
polyclonal
Host Species
Rabbit
Reactive Species
human, mouse, rat
Isotype
n/a
Format
immunogen affinity purified
Size
100 μg
Concentration
n/a
Applications
Western Blotting (WB),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Reviews / Ratings
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Description
Neutral amino acid transporter A, also called SLC1A4 or ASCT1, is a protein that in humans is encodes by the SLC1A4 gene. The SLC1A4 gene is mapped to chromosome 2p14 based on an alignment of the SLC1A4 sequence with the genomic sequence(GRCh37). ASCT1 does not transport glutamate or aspartate but alanine, serine, cysteine, and threonine instead. It is found that the ASCT1 transporter functions primarily as an amino acid exchanger. Transport is associated with a chloride channel activity that is thermodynamically uncoupled from animo acid transport. This gene also exhibits sodium dependence.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human SLC1A4(495-512aa EAIPNCKSEEETSPLVTH), different from the related rat and mouse sequences by one amino acid.