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Description
VGLUT1 Polyclonal Antibody. VGLUT1 (Vesicular Glutamate Transporter 1, BNPI, SLC17A7) protein is a vesicle-bound, sodium-dependent inorganic phosphate transporter that functions as a vesicular glutamate transporter and may be involved in neuronal sodium transport. Vesicular glutamate transporters VGLUT1 and VGLUT2 show a mutually exclusive distribution in the adult brain that suggests specialization for synapses with different properties of release. Consistent with this distribution, inactivation of the VGLUT1 gene silenced a subset of excitatory neurons in the adult brain. The targeted deletion of VGLUT1 in mice caused lethality in the third postnatal week, a time when there is a developmental switch from VGLUT2 to VGLUT1 expression. Gluta
Immunogen
n/a
Other Names
Vesicular glutamate transporter 1, VGlU1, Solute carrier family 17 member 7, Brain-specific Na(+)-dependent inorganic phosphate cotransporter, Bnpi