Immunocytochemistry: 1:200, Immunofluorescence: 1:200, Western Blot: 1:1000
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Description
SKP2 Polyclonal Antibody. This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class; in addition to an F-box, this protein contains 10 tandem leucine-rich repeats. This protein is an essential element of the cyclin A-CD
Immunogen
n/a
Other Names
CDK2/cyclin A-associated protein p45; F-box protein Skp2; F-box/LRR-repeat protein 1; OTTHUMP00000221389; S-phase kinase-associated protein 2; cyclin A/CDK2-associated protein p45; cyclin-A/CDK2-associated protein p45; p45skp2