NHP2L1 is a component of the spliceosome complex. It is recruited to introns following the attachment of U4 and U6 RNAs, and is required for subsequent recruitment of PRP31 and activation of the spliceosomal complex . In the course of sequencing cDNA clones from fetal brain cDNA libraries, Saito et al. (1996) isolated a gene that encodes a protein highly homologous to NHP2 from Saccharomyces cerevisiae (Kolodrubetz and Burgum, 1991). NHP2 is a high-mobility group (HMG)-like protein which is loca
[NHP2-like protein 1; NHP2-like protein 1; NHP2-like protein 1; small nuclear ribonucleoprotein 13; High mobility group-like nuclear protein 2 homolog 1; U4/U6.U5 small nuclear ribonucleoprotein SNU13]