GW 7647 is a potent, selective agonist of human and murine PPARα{14085} It activates human PPARα, PPARγ, and PPAR.delta. with EC50 values of 0.006, 1.1 and 6.2 μM, respectively, in a GAL4-PPAR binding assay. Similar EC50 values of 0.001, 1.3, and 2.9 were observed with the murine receptors. GW 7647 lowered triglycerides 93% and 60% in fat-fed hamsters and rats, respectively, at a dose of 3 mg/kg.{14085}
Size
1 mg
Concentration
n/a
Applications
n/a
Other Names
PPARa PPARg PPARd PPAR-α γ FA GAL4PPAR GAL-4 δ GW7647