Binds avidly and selectively to the structurally-similar bromodomains of SMARCA4 and PB1(domain 5) with Kd values of 89 and 48 nM, respectively; also interacts with the bromodomain of SMARCA2; does not interact with other bromodomains or with a panel of kinases
Size
25 mg
Concentration
n/a
Applications
n/a
Other Names
epigenetics inhibitors chromatin research genes regulations inhibits inhibitions probes bromodomains SMARCA2 SMARCA4 SMARCAs 2 4 SMARCs proteins PFI3 PFIs 3 three PB1 PB-1 PBs 1 one 5 five thermal stability assays two four kinases Structural Genomic Consortium SGC BRG1 BRG