Recombinant Human DNA replication licensing factor MCM2 (MCM2)
Description
Purity > 90% as determined by SDS-PAGE. MW: 105.8kDa. Full Length of Mature Protein: 2-904aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division.
Size
100ug
Concentration
n/a
Applications
RUO
Other Names
Minichromosome maintenance protein 2 homologNuclear protein BM28