Purity > 90% as determined by SDS-PAGE. MW: 55.8kDa. Full Length of Isoform 2: 1-366aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Plays a role in modulating cellular differentiation.