A potent inhibitor of the PI3K catalytic subunit p110δ (IC50s = 10,000, 490, 10, and 160 nM, for p110 subunit isoforms α, β, δ, and γ, respectively); selective for PI3K p110 subunit isoforms over DNA-PK, mTOR, and eight tyrosine kinases; inhibits chemokinetic and chemotactic migration of neutrophils induced by CXCL8