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Description
Mouse Anti-BRCA2 Recombinant Antibody (CBYY-0791). This product is mouse antibody that recognizes BRCA2. The antibody CBYY-0791 can be used for immunoassay techniques such as: WB. Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Bovineth BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) o
Immunogen
n/a
Other Names
BRCA2, DNA Repair Associated; BRCA1/BRCA2-Containing Complex, Subunit 2; Fanconi Anemia Group D1 Protein; Breast Cancer 2, Early Onset; FANCD1; FACD; Breast And Ovarian Cancer Susceptibility Gene, Early Onset; Breast And Ovarian Cancer Susceptibility Protein 2; Breast Cancer Type 2 Susceptibility Protein; Fanconi Anemia, Complementation Group D1; Breast Cancer 2 Tumor Suppressor; Truncated Breast Cancer 2;