A selective inhibitor of Plk1 (IC50 = 0.83 nM); induces mitotic arrest and apoptosis in diverse human cancer cell lines and drives regression of human tumor xenografts in nude mice; also an inhibitor of BRD4 (IC50 = 25 nM)
Size
10 mg
Concentration
n/a
Applications
n/a
Other Names
1073158-33-4 biochemical inhibitor protein kinase intracellular signaling cell cycle cancer chromatin research epigenetics histone modification inhibit BI2536 (R)-BI2536 polo-like Plk1 Plk-1