Nitric oxide synthases (NOS) are a family of enzymes that catalyze the production of nitric oxide (NO) from L-arginine. Nitric oxide (NO) plays an important role in neurotransmission, vascular regulation, immune response and apoptosis. In presence of NADPH, FAD, FMN, (6R)-5,6,7,8-tetrahydrobiopterin, calmodulin and heme, NOS catalyzes a five-electron oxidation of the guanidino nitrogen of L-arginine with molecular oxygen to generate NO and L-citrulline. There are three isoforms of NOS: endothelial (eNOS), neuronal (nNOS), and inducible (eNOS). eNOS produces NO in blood vessels and is involved in regulation of vascular function. BioVision's NOS3 ELISA kit is a sandwich ELISA assay for the quantitative measurement of NOS3 in mouse serum, plas
Size
96 assays
Concentration
n/a
Applications
This ELISA kit is used for quantitative measurement of NOS3 in serum, plasma, tissue homogenates and other biological fluids.