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Description
Mouse Anti-CD46 Recombinant Antibody (D3/9). This product is a mouse antibody that recognizes CD46. The antibody D3/9 can be used for immunoassay techniques such as: FC. MCP, a C3B/C4B-binding molecule of the complement system with cofactor activity for the I-dependent cleavage of C3B and C4B, is widely distributed in white blood cells, platelets, epithelial cells, and fibroblasts. CD46 acts as a cellular receptor for type IV pili of pathogenic Neisseria. The binding of piliated bacteria to host cells can be inhibited by antibody to CD46 or the recombinant molecule. Kallstrom et al. (2001) showed that the BC1 phenotype of the STP domain as well as the complement control protein repeat 3 (CCP3) of CD46 are important for efficient adherence o