Recombinant Human Very long-chain acyl-CoA synthetase (SLC27A2), partial
Description
Purity > 90% as determined by SDS-PAGE. MW: 40.8kDa. Cytoplasmic Domain: 283-620aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across mbranes.
Size
100ug
Concentration
n/a
Applications
RUO
Other Names
Fatty acid transport protein 2; FATP-2Fatty-acid-coenzyme A ligase, very long-chain 1Long-chain-fatty-acid--CoA ligase (EC:6.2.1.3)Solute carrier family 27 member 2THCA-CoA ligaseVery long-chain-fatty-acid-CoA ligase