Exemestane is a potent, irreversible steroidal aromatase inhibitor (Ki = 10.2 nM; Kinact = 26 nM). It induces aromatase degradation leading to a decrease in estrogen levels in plasma. As an androgen analog, exemestane displays androgenic effects and has been shown to decrease total and HDL cholesterol, apo A1, and total triglyceride levels. MW: 296.4. Purity ≥95%