26-132. MW: 39.1kD. Purity >90% as determined by SDS-PAGE. Acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G. May prevent elastase-mediated damage to oral and possibly other mucosal tissues.
Molecular cloning and expression of cDNA for human antileukoprotease from cervix uterus.Heinzel R., Appelhans H., Gassen G., Seemueller U., Machleidt W., Fritz H., Steffens G.Eur. J. Biochem. 160:61-67(1986) Isolation and sequence of a human gene encoding a potent inhibitor of leukocyte proteases.Stetler G., Brewer M.T., Thompson R.C.Nucleic Acids Res. 14:7883-7896(1986) Cloning and characterization of SLPI from human intestinal epithelium.Si-Tahar M., Merlin D., Sitaraman S., Madara J.L. Comple