A retinoid; increases the doubling time and transcription of RARβ mRNA in various human oral squamous cell carcinoma cells at 1 μM; inhibits proliferation of primary human sebocytes (IC50 = 10 μM); decreases triglyceride, stearyl ester, and free fatty acid synthesis and modulates keratin expression in primary human sebocytes at 0.1 μM; reduces chronic rejection damage and decreases mRNA expression of IFN-γ and IL-10 in allografts in chronic Fisher344?Lewis transplant mice at 2 mg/kg per day; slows rod and cone recovery and prevents light-induced photoreceptor damage in an albino rat model of photoreceptor degeneration at 40 mg/kg
Size
5 g
Concentration
n/a
Applications
n/a
Other Names
13(Z)-Retinoic Acid|13-cis-Vitamin A Acid|AGN 190013