Flow Cytometry: 1:25, Immunoprecipitation: 1:50, Western Blot: 1:1000
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Description
THEM4 Polyclonal Antibody. Protein kinase B (PKB) is a major downstream target of receptor tyrosine kinases that signal via phosphatidylinositol 3-kinase. Upon cell stimulation, PKB is translocated to the plasma membrane, where it is phosphorylated in the C-terminal regulatory domain. The protein encoded by this gene negatively regulates PKB activity by inhibiting phosphorylation. Transcription of this gene is commonly downregulated in glioblastomas.
Immunogen
n/a
Other Names
C-terminal modulator protein; carboxyl-terminal modulator protein