A potent, selective inhibitor of HDAC6 (IC50 = 56 nM); induces acetylation of α-tubulin but not histones; enhances the cytotoxicity of the broad spectrum HDAC inhibitor SAHA against cancer cells in nude mice carrying an androgen-dependent CWR22 human prostate cancer xenograft
Size
1 mg
Concentration
n/a
Applications
n/a
Other Names
biochemical inhibitor cancer histone deacetylase cytoskeletal research HDAC6 HDAC 6 acetylation α-tubulin SAHA