Recombinant Human C-X-C motif chemokine 5 protein (CXCL5) (Active)
Description
Purity > 90% as determined by SDS-PAGE. MW: 60.6kDa. Extracellular Domain: 33-320aa. C-terminal FC-tagged. Homo sapiens (Human). Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure.