Cytokeratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. Alternative Names: Cytokeratin 18 protein, Cytokeratin 18, Cytokeratin-18 protein, Cytokeratin-18, Keratin K18 protein, Cytokeratin 18